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Cancer nanomedicine

A photo-controlled charge regulator improves cancer theranostics

Nature Nanotechnology (2024)Cite this article

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Photobleaching-harnessing charge conversion initiates nanomedicine transcytosis, improving therapeutic outcomes in various rectal tumour mouse models.

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Fig. 1: Photobleaching-mediated charge-convertible nanoparticles for rectal tumour treatment.

adapted from ref. 2, Springer Nature Ltd.

References

  1. Blanco, E., Shen, H. & Ferrari, M. Nat. Biotechnol. 33, 941–951 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Nguyen, D.-T. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-024-01757-4 (2024).

    Article  PubMed  Google Scholar 

  3. Mitchell, M. J., Jain, R. K. & Langer, R. Nat. Rev. Cancer 17, 659–675 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Nguyen, L. N. M. et al. Nat. Rev. Bioeng. 2, 201–213 (2024).

    Article  Google Scholar 

  5. Pandit, S., Dutta, D. & Nie, S. Nat. Mater. 19, 478–480 (2020).

    Article  CAS  PubMed  Google Scholar 

  6. Baek, M.-J. et al. Nat. Nanotechnol. 18, 945–956 (2023).

    Article  CAS  PubMed  Google Scholar 

  7. Chen, S. et al. Nat. Biomed. Eng. 5, 1019–1037 (2021).

    Article  CAS  PubMed  Google Scholar 

  8. Lu, Y. et al. Nat. Biomed. Eng. 2, 318–325 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Zhang, Y. et al. ACS Nano 17, 16743–16756 (2023).

    Article  CAS  PubMed  Google Scholar 

  10. Zhou, Q. et al. Nat. Nanotechnol. 14, 799–809 (2019).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, China

    Shan Lei & Peng Huang

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  1. Shan Lei
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  2. Peng Huang
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Correspondence to Peng Huang.

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The authors declare no competing interests.

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Lei, S., Huang, P. A photo-controlled charge regulator improves cancer theranostics. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01745-8

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