Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Drug delivery

Mitochondrial transplantation for ischemic heart disease

Mitochondrial transplantation with engineered nanomotorized mitochondria permits increased trafficking to ischemic heart tissue and recovery of cardiac function.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Treatment of myocardial infarction with CM/NM/Mito@Cap.

References

  1. Cardiovascular Disability: Updating the Social Security Listings (National Academy of Sciences, 2010).

  2. Wu, Z. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-024-01681-7 (2024).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Huang, Y. & Zhou, B. Biomedicines 11, 1500 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Norat, P. et al. npj Regen. Med. 5, 22 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Emani, S. M., Piekarski, B. L., Harrild, D., del Nido, P. J. & McCully, J. D. J. Thorac. Cardiovasc. Surg. 154, 286–289 (2017).

    Article  PubMed  Google Scholar 

  6. Guariento, A. et al. J. Thorac. Cardiovasc. Surg. 162, 992–1001 (2021).

    Article  PubMed  Google Scholar 

  7. Cowper, P. A. et al. J. Am. Heart Assoc. 8, e011322 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Catherine Gorick.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gorick, C., Debski, A. Mitochondrial transplantation for ischemic heart disease. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01678-2

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41565-024-01678-2

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research