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All the lonely atoms, where do they all belong?

A spectacular advance in catalyst synthesis is demonstrated by a two-step process that yields high loadings of single atoms at a kilogram scale suitable for industrial deployment.

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Fig. 1: Evolution in the synthesis of supported metal catalysts.


  1. Regalbuto, J. R. in Catalyst Preparation: Science and Engineering (ed. Regalbuto, J. R.) Ch. 13 (Taylor and Francis/CRC Press, 2007).

  2. Wong, A., Liu, Q., Griffin, S., Nicholls, A. & Regalbuto, J. R. Science 358, 6369 (2017).

    Article  Google Scholar 

  3. Jones, J. et al. Science 353, 150–154 (2016).

    Article  CAS  Google Scholar 

  4. Pham, H., Sattler, J., Weckhuysen, B. & Datye, A. ACS Catal. 6, 2257–2264 (2016).

    Article  CAS  Google Scholar 

  5. Peterson, E. J. et al. Nat. Commun. 5, 4885 (2014).

    Article  CAS  Google Scholar 

  6. Sun, T., Xu, L., Wang, D. & Li, Y. Nano Res. 12, 2067–2080 (2019).

    Article  CAS  Google Scholar 

  7. Liu, L. C. & Corma, A. Nat. Rev. Mater. 6, 244–263 (2021).

    Article  CAS  Google Scholar 

  8. Hai. et al. Nat. Nanotechnol. (2021).

  9. DeRita, L. et al. Nat. Mater. 18, 746–751 (2019).

    Article  CAS  Google Scholar 

  10. Datye, A. K. & Guo, H. Nat. Commun. 12, 895 (2021).

    Article  CAS  Google Scholar 

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Correspondence to John R. Regalbuto or Abhaya K. Datye.

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The author declares no competing interests.

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Regalbuto, J.R., Datye, A.K. All the lonely atoms, where do they all belong?. Nat. Nanotechnol. 17, 110–111 (2022).

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