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A DNA nanodevice boosts tumour immunity

A DNA nanodevice that selectively modulates the lysosomal protease activity in tumour-associated macrophages, increasing their antigen presentation ability, attenuates tumour growth in vivo.

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Fig. 1: Designer DNA nanodevice for the enhancement of anti-tumour immunity.


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Correspondence to Jiang Li or Chunhai Fan.

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The authors declare no competing interests.

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Li, J., Fan, C. A DNA nanodevice boosts tumour immunity. Nat. Nanotechnol. (2021).

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