Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

ELECTROCHEMICAL NEUROMODULATION

Electrochemical cell in the brain

Nitric oxide, a gaseous neurotransmitter, can be electrochemically generated inside the brain to activate calcium ion channels, paving the way for implantable neurotransmitter probes.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Neuronal stimulation by an implanted NO-delivery probe.

References

  1. Bullmore, E. & Sporns, O. Nat. Rev. Neurosci. 10, 186–198 (2009).

    Article  CAS  Google Scholar 

  2. Abbott, J. et al. Nat. Biomed. Eng. 4, 232–241 (2020).

    Article  CAS  Google Scholar 

  3. Ueda, H. R. et al. Nat. Rev. Neurosci. 21, 61–79 (2020).

    Article  CAS  Google Scholar 

  4. Calabrese, V. et al. Nat. Rev. Neurosci. 8, 766–775 (2007).

    Article  CAS  Google Scholar 

  5. Park, J. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-020-0701-x (2020).

  6. Lundberg, J. O., Weitzberg, E. & Gladwin, M. T. Nat. Rev. Drug Discov. 7, 156–167 (2008).

    Article  CAS  Google Scholar 

  7. He, D. et al. J. Am. Chem. Soc. 140, 2012–2015 (2018).

    Article  CAS  Google Scholar 

  8. Kim, C. K., Adhikari, A. & Deisseroth, K. Nat. Rev. Neurosci. 18, 222–235 (2017).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ki Tae Nam.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nam, K.T., Park, S. Electrochemical cell in the brain. Nat. Nanotechnol. 15, 625–626 (2020). https://doi.org/10.1038/s41565-020-0711-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41565-020-0711-8

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research