Electrochemical cell in the brain

Nitric oxide, a gaseous neurotransmitter, can be electrochemically generated inside the brain to activate calcium ion channels, paving the way for implantable neurotransmitter probes.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1: Neuronal stimulation by an implanted NO-delivery probe.


  1. 1.

    Bullmore, E. & Sporns, O. Nat. Rev. Neurosci. 10, 186–198 (2009).

    CAS  Article  Google Scholar 

  2. 2.

    Abbott, J. et al. Nat. Biomed. Eng. 4, 232–241 (2020).

    CAS  Article  Google Scholar 

  3. 3.

    Ueda, H. R. et al. Nat. Rev. Neurosci. 21, 61–79 (2020).

    CAS  Article  Google Scholar 

  4. 4.

    Calabrese, V. et al. Nat. Rev. Neurosci. 8, 766–775 (2007).

    CAS  Article  Google Scholar 

  5. 5.

    Park, J. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-020-0701-x (2020).

  6. 6.

    Lundberg, J. O., Weitzberg, E. & Gladwin, M. T. Nat. Rev. Drug Discov. 7, 156–167 (2008).

    CAS  Article  Google Scholar 

  7. 7.

    He, D. et al. J. Am. Chem. Soc. 140, 2012–2015 (2018).

    CAS  Article  Google Scholar 

  8. 8.

    Kim, C. K., Adhikari, A. & Deisseroth, K. Nat. Rev. Neurosci. 18, 222–235 (2017).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Ki Tae Nam.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Nam, K.T., Park, S. Electrochemical cell in the brain. Nat. Nanotechnol. (2020). https://doi.org/10.1038/s41565-020-0711-8

Download citation