Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

ELECTROPHYSIOLOGY

Curving neural nanobioelectronics

Nature Nanotechnology volume 14, pages 733–735 (2019)Cite this article

Subjects

Three-dimensional nanowire transistors with curvilinear tips record intracellular signals from neurons.

Writing in Nature Nanotechnology, Zhao et al. reveal the promise for curved inorganic nanostructures as neural recording devices3. The authors integrate a curvature element into a nanowire-based field-effect transistor (NWFET) and demonstrate that this curved element is critical for neuronal intracellular entry and subsequent electrical recordings. Prior studies have demonstrated that nanostructures can produce responses from curvature-sensing membrane proteins and that nanostructure geometries can affect their internalization dynamics2.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Curvature matters in nanobioelectronics.

References

  1. Thompson, D. W. On Growth and Form: The Complete Revised Edition (Dover, 1992).

  2. Tian, B. & Lieber, C. M. Chem. Rev. https://doi.org/10.1021/acs.chemrev.8b00795 (2019).

  3. Zhao, Y. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-019-0478-y (2019).

  4. Shi, Z., Graber, Z. T., Baumgart, T., Stone, H. A. & Cohen, A. E. Cell 175, 1769–1779.e13 (2018).

    Article  CAS  Google Scholar 

  5. Groves, J. T. Dev. Cell 48, 15–16 (2019).

    Article  CAS  Google Scholar 

  6. Diz-Muñoz, A., Weiner, O. D. & Fletcher, D. A. Nat. Phys. 14, 648–652 (2018).

    Article  Google Scholar 

  7. Xiang, L., Chen, K., Yan, R., Li, W. & Xu, K. Preprint at https://doi.org/10.1101/559484 (2019).

  8. Saminathan, A. et al. Preprint at https://doi.org/10.1101/523019 (2019).

  9. Perea, D. E., Gerstl, S. S. A., Chin, J., Hirschi, B. & Evans, J. E. Adv. Struct. Chem. Imaging 3, 12 (2017).

    Article  Google Scholar 

  10. Deng, J. et al. Sci. Adv. 4, eaau4548 (2018).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. James Franck Institute, University of Chicago, Chicago, IL, USA

    Yin Fang & Bozhi Tian

Authors
  1. Yin Fang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bozhi Tian
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Yin Fang or Bozhi Tian.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fang, Y., Tian, B. Curving neural nanobioelectronics. Nat. Nanotechnol. 14, 733–735 (2019). https://doi.org/10.1038/s41565-019-0503-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41565-019-0503-1

Search

Advanced search

Quick links

Find nanotechnology articles, nanomaterial data and patents all in one place. Visit Nano by Nature Research