Supplementary Fig. 40 | Nature Nanotechnology

Supplementary Fig. 40

From: Author Correction: Magnesium silicide nanoparticles as a deoxygenation agent for cancer starvation therapy

Supplementary Fig. 40

Representative confocal images of the intracellular O2 level indicator [Ru(dpp)3]Cl2-stained MCF-7 cells after treatments in different culture media of pH = 7.4 or 6.5 and co-incubated with varied concentrations of MS NPs (0, 2, 5 and 10 mM) for 2 h. Scale bars, 50 µm. Note that the status of cell adherence is a little different between the two independent experiments, but it doesn’t affect the qualitative fluorescence assessment. The increased red fluorescence indicates a decrease in the intracellular oxygen level. The result further confirms that the acidity-activated deoxygenating effect of MS NPs on the cells is repeatable.

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