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A synthetic lethal bullet

Nanoparticles loaded with paclitaxel and nintedanib induce synthetic lethality in endometrial cancer cells.

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Fig. 1: TPGS–PLGA nanoparticles loaded with nintedanib and paclitaxel extravasate through the leaky tumour vasculature and reach tumour cells.


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Correspondence to Christian Rolfo or Elisa Giovannetti.

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Rolfo, C., Giovannetti, E. A synthetic lethal bullet. Nature Nanotech 13, 6–7 (2018).

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