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Host–gut microbiota crosstalk predicts neuroinflammation

Nature Microbiology volume 9, pages 2204–2205 (2024)Cite this article

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Microbial networks and host–microbiota interactions, especially immunoglobulin A coating of resident microbiota, outperform bacterial abundance as a predictor of neuroinflammation severity in a mouse model of multiple sclerosis.

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Fig. 1: IgA-coated microbiota predicts EAE progression.

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Authors and Affiliations

  1. Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Carolina M. Polonio & Francisco J. Quintana

  2. Broad Institute of MIT and Harvard, Cambridge, MA, USA

    Francisco J. Quintana

  3. Gene Lay Institute of Immunology and Inflammation, Brigham and Women’s Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Francisco J. Quintana

Authors
  1. Carolina M. Polonio
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  2. Francisco J. Quintana
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Correspondence to Francisco J. Quintana.

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The authors declare no competing interests

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Polonio, C.M., Quintana, F.J. Host–gut microbiota crosstalk predicts neuroinflammation. Nat Microbiol 9, 2204–2205 (2024). https://doi.org/10.1038/s41564-024-01790-y

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