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Microbial regulation of cholesterol homeostasis


Commensal gut bacteria harbour sulfotransferases that metabolize cholesterol and some steroid hormones to produce bacterially derived signals that influence host phenotypes.

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Fig. 1: Commensal gut microbes shape cholesterol homeostasis.


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Correspondence to William J. Massey or J. Mark Brown.

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Massey, W.J., Brown, J.M. Microbial regulation of cholesterol homeostasis. Nat Microbiol 7, 1327–1328 (2022).

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