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MICROBIOME

Gut–bladder axis in recurrent UTI

Dysbiosis of the gut microbiome is associated with increased susceptibility to recurrent urinary tract infection, defining a gut–bladder axis.

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Fig. 1: The gut–bladder axis and its role in recurrent UTI.

References

  1. Zowawi, H. M. et al. Nat. Rev. Urol. 12, 570–584 (2015).

    CAS  Article  Google Scholar 

  2. Forde, B. M. et al. Nat. Commun. 10, 3643 (2019).

    Article  Google Scholar 

  3. Cryan, J. F. et al. Physiol. Rev. 99, 1877–2013 (2019).

    CAS  Article  Google Scholar 

  4. Budden, K. F. et al. Nat. Rev. Microbiol. 15, 55–63 (2017).

    CAS  Article  Google Scholar 

  5. Worby, C. J. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-022-01107-x (2022).

    Article  PubMed  Google Scholar 

  6. Integrative HMP Research Network Consortium. Cell Host Microbe 16, 276–289 (2014).

    Article  Google Scholar 

  7. Petty, N. K. et al. Proc. Natl Acad. Sci. USA 111, 5694–5699 (2014).

    CAS  Article  Google Scholar 

  8. Shevchenko, S. G. et al. Appl. Environ. Microbiol. 85, 23 (2019).

    Article  Google Scholar 

  9. Okamoto, T. et al. World J. Urol. 39, 847–853 (2021).

    CAS  Article  Google Scholar 

  10. Chen, Z. et al. Int. Urogynecol. J. 29, 1775–1782 (2018).

    Article  Google Scholar 

Download references

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Correspondence to Mark A. Schembri.

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Schembri, M.A., Nhu, N.T.K. & Phan, MD. Gut–bladder axis in recurrent UTI. Nat Microbiol 7, 601–602 (2022). https://doi.org/10.1038/s41564-022-01113-z

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  • DOI: https://doi.org/10.1038/s41564-022-01113-z

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