Immunologic recognition of bacterial products during skin infection triggers a cytokine and chemokine response that facilitates neutrophil recruitment to the site of infection. Staphylococcus aureus phenol-soluble modulins can function as early chemoattractants to directly recruit neutrophils and alert the host to infection.
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J.B.W. has a financial agreement with Aridis Pharmaceuticals related to patents owned by the University of Chicago.
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Fogel, L.A., Bubeck Wardenburg, J. Staphylococcus aureus PSMs are a double-edged sword. Nat Microbiol 7, 12–13 (2022). https://doi.org/10.1038/s41564-021-01040-5
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DOI: https://doi.org/10.1038/s41564-021-01040-5