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Malaria parasite beats the heat

The malaria parasite Plasmodium falciparum survives fever during human infection by using a transcription factor to regulate its heat-shock response.

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Fig. 1: The ApiAP2 transcription factor PfAP2-HS drives activation of essential heat-shock responses in P. falciparum–infected red blood cells.


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Correspondence to David A. Fidock.

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Thathy, V., Fidock, D.A. Malaria parasite beats the heat. Nat Microbiol 6, 1105–1107 (2021).

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