Extended Data Fig. 6: Effects of Sec24C KD on infectivity of HIV-1 (WT CA) and HIV-1 (N74D CA). | Nature Microbiology

Extended Data Fig. 6: Effects of Sec24C KD on infectivity of HIV-1 (WT CA) and HIV-1 (N74D CA).

From: Sec24C is an HIV-1 host dependency factor crucial for virus replication

Extended Data Fig. 6

a, Representative immunoblot for the siRNA-mediated KD of Sec24C in HeLa cells. b and c, Infectivity (normalized to negative control KD) of VSV-G pseudotyped HIV-1 virus in WT and Sec24C KD HeLa cells without (b) and with (c) 1 µg/ml Aphidicolin. d-e, Infectivity (normalized to negative control KD) of VSV-G pseudotyped HIV-1 N74D CA mutant virus in WT and Sec24C KD HeLa cells without (d) and with (e) 1 µg/ml Aphidicolin. The data (mean values ± SD) from three independent experiments are shown. Statistical significance was determined by two-tailed student t-test.

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