Extended Data Fig. 3: Priors and posteriors for evolutionary rate of SARS-CoV-2. | Nature Microbiology

Extended Data Fig. 3: Priors and posteriors for evolutionary rate of SARS-CoV-2.

From: Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

Extended Data Fig. 3

Posterior rate distributions for MERS-CoV (far left) and HCoV-OC43 (far right) using BEAST on n = 27 sequences spread over 4 years (MERS-CoV) and n = 27 sequences spread over 49 years (HCoV-OC43). As illustrated by the dashed arrows, these two posteriors motivate our specification of prior distributions with standard deviations inflated 10-fold (light color). These rate priors are subsequently used in the Bayesian inference of posterior rates for NRR1, NRR2, and NRA3 as indicated by the solid arrows.

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