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Treat phage like living antibiotics

Bacteriophage therapeutics has emerged as one of the few potential beacons that represent possible solutions to the growing global crisis of antimicrobial resistance. Bringing science to the bedside (and vice versa) will maximize the potential of this compelling opportunity.

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Fig. 1: Phage evolution: from sideshow to centre stage.


  1. Rohwer, F., Maughan, H., Youle, M. & Hisakawa, N. Life in Our Phage World: A Centennial Field Guide to the Earth’s Most Diverse Inhabitants (Wholon, 2014).

  2. Summers, W. C. Bacteriophage 2, 130–133 (2012).

    Article  Google Scholar 

  3. Wommack, K. E. & Colwell, R. R. Microbiol. Mol. Biol. Rev. 64, 69–71 (2000).

    Article  CAS  Google Scholar 

  4. Locey, K. J. & Lennon, J. T. Proc. Natl Acad. Sci. USA 24, 5970–5975 (2016).

    Article  Google Scholar 

  5. Twort, F. W. Lancet 186, 1241–1243 (1915).

    Article  Google Scholar 

  6. Fabijan, A. P. et al. Nat. Microbiol. (2020).

  7. Doogue, M. P. & Polasek, T. M. Ther. Adv. Drug Saf. 4, 5–7 (2013).

    Article  Google Scholar 

  8. Ramratnam, B. et al. Nat. Med. 6, 82–85 (2000).

    Article  CAS  Google Scholar 

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Correspondence to Robert T. Schooley.

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Competing interests

R. T. S. serves as a consultant to CytoDyn and has stock options in CytoDyn and Antiva Biosciences. He is a member of the Gilead Sciences Scientific Advisory Board and previously served as an uncompensated member of the AmpliPhi Scientific Advisory Board. S. S. holds stock in Adaptive Phage Therapeutics and is an uncompensated scientific advisor to NextBiotics.

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Schooley, R.T., Strathdee, S. Treat phage like living antibiotics. Nat Microbiol 5, 391–392 (2020).

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