Extended Data Fig. 2: Validation on a simulated microbial community. | Nature Microbiology

Extended Data Fig. 2: Validation on a simulated microbial community.

From: Tracking microbial evolution in the human gut using Hi-C reveals extensive horizontal gene transfer, persistence and adaptation

Extended Data Fig. 2

The genomes of 55 common gut microbes (GOLD database) were downloaded and 120 M simulated shotgun reads and 100 M simulated Hi-C reads were generated, with relative representation ranging from 1 to 1000. HPIPE identified 32 MAGs. Shown is the density plot of the relative abundance of the entire metagenomic assembly (contigs >1k), as in Fig. 1d. The abundance is the enrichment of the read coverage over a uniform distribution of reads. White/gray stripes denote chunks of 10 Mb. The fraction of the assembly that was included in any recovered MAG (‘anchored contigs’) is depicted with a red line.

Back to article page