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ANTIMICROBIALS

Anti-psychotic drugs block meningococcal virulence

Nature Microbiology volume 4, pages 906–907 (2019)Cite this article

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A class of drugs approved to treat schizophrenia can cause rapid loss of the pilus, an essential virulence factor necessary for the disease-causing properties in the strict human pathogen Neisseria meningitidis.

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Fig. 1: Phenothiazines inhibit T4p functions.

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  1. Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    H Steven Seifert

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  1. H Steven Seifert
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Correspondence to H Steven Seifert.

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Seifert, H.S. Anti-psychotic drugs block meningococcal virulence. Nat Microbiol 4, 906–907 (2019). https://doi.org/10.1038/s41564-019-0467-9

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