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A powerful, non-invasive test to rule out infection

Rapid diagnostic tests capable of detecting any potential pathogen are needed to improve the efficacy of antimicrobial therapy and inform antimicrobial stewardship efforts. A new metagenomics-based test that detects microbial DNA in human blood can identify a diverse array of pathogens from any source in the body.

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Fig. 1: Metagenomic detection of microbial cfDNA for infection diagnosis.


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Correspondence to Justin O’Grady.

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J.O'G. received free sequencing consumables, expenses for conference attendance and research funding from Oxford Nanopore Technologies.

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O’Grady, J. A powerful, non-invasive test to rule out infection. Nat Microbiol 4, 554–555 (2019).

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