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Harnessing undomesticated life

Nature Microbiologyvolume 4pages212213 (2019) | Download Citation

Only a tiny fraction of bacterial species can be cultured and engineered in the laboratory, limiting our ability to deploy bacteria in harsh environments or use them to produce important compounds. Recent work has opened this frontier by developing new methods to characterize and engineer diverse, undomesticated bacterial species.

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Author information


  1. Department of Systems Biology, Harvard Medical School, Boston, MA, USA

    • Elizabeth A. Libby
    •  & Pamela A. Silver
  2. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA

    • Elizabeth A. Libby
    •  & Pamela A. Silver


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Competing interests

The authors declare no competing interests.

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Correspondence to Pamela A. Silver.

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