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APOBEC restriction goes nuclear

Nature Microbiologyvolume 4pages67 (2019) | Download Citation

APOBEC3 restriction, known to inhibit retroviruses by interfering with genome replication and hypermutating viral DNA, targets the γ-herpesvirus Epstein–Barr virus and is antagonized by the viral BORF2 protein.

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Author information


  1. Department of Infectious Diseases, School of Immunology and Microbial Sciences, King’s College London, London, UK

    • Michael H. Malim
    •  & Darja Pollpeter


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The authors declare no competing interests.

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Correspondence to Michael H. Malim or Darja Pollpeter.

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