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VIRAL IMMUNE RESPONSE

Dusting for flu’s fingerprints

Nature Microbiology volume 3, pages 1196–1197 (2018)Cite this article

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A key step of the antiviral immune response is detection of the viral intruder. Infection with highly pathogenic strains of influenza virus is now shown to produce short aberrant viral RNAs that potently trigger activation of innate immunity.

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Fig. 1: Infection by high-pathogenicity IAV strains results in the production of mvRNAs that activate innate immunity via the pathogen sensor RIG-I.

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  1. Department of Microbiology, The University of Chicago, Chicago, IL, USA

    William Riedl & Michaela U. Gack

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  1. William Riedl
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  2. Michaela U. Gack
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Correspondence to Michaela U. Gack.

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The authors declare no competing interests.

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Riedl, W., Gack, M.U. Dusting for flu’s fingerprints. Nat Microbiol 3, 1196–1197 (2018). https://doi.org/10.1038/s41564-018-0270-z

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