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PARASITE BIOLOGY

The perplexing PEXEL protein secretory pathway

Nature Microbiology volume 3, pages 969–970 (2018)Cite this article

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Plasmodium parasites possess a unique PEXEL sorting pathway to deliver secretory proteins into the host cells in which they reside. A new study shows the existence of independent sorting/entry complexes to detect and deliver PEXEL proteins into the parasite endoplasmic reticulum.

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Fig. 1: Plasmodium protein secretion pathways.

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Authors and Affiliations

  1. School of Biological Sciences, Faculty of Biology Medicine and Health, Health Innovation Manchester, University of Manchester, Manchester, UK

    Martin R. Pool

  2. Infectious Diseases, Washington University School of Medicine, St Louis, MO, USA

    Ilaria Russo

Authors
  1. Martin R. Pool
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  2. Ilaria Russo
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Correspondence to Martin R. Pool or Ilaria Russo.

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The authors declare no competing interests.

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Pool, M.R., Russo, I. The perplexing PEXEL protein secretory pathway. Nat Microbiol 3, 969–970 (2018). https://doi.org/10.1038/s41564-018-0235-2

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