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STING’ing Zika virus in neurons

Nature Microbiology volume 3, pages 975–976 (2018)Cite this article

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Studies in Drosophila reveal that the insect homologue of the stimulator of interferon genes (STING) exerts antiviral activity against Zika virus infection in the fly brain through the induction of autophagy, providing key insights into the possible evolutionary function of STING in antiviral defence.

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Authors and Affiliations

  1. Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Carolyn B. Coyne

  2. Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Carolyn B. Coyne

  3. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Carolyn B. Coyne

  4. Center for Microbial Pathogenesis, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Carolyn B. Coyne

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  1. Carolyn B. Coyne
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Correspondence to Carolyn B. Coyne.

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The authors declare no competing interests.

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Coyne, C.B. STING’ing Zika virus in neurons. Nat Microbiol 3, 975–976 (2018). https://doi.org/10.1038/s41564-018-0232-5

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  • DOI: https://doi.org/10.1038/s41564-018-0232-5

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