Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

MICROBIOME

Microbial metabolic gatekeeping in the jejunum

Nature Microbiology volume 3, pages 650–651 (2018)Cite this article

Subjects

The small intestine microbiome has been revealed to play a critical role in nutritional signal transduction that enables the host to adapt its fat digestion and absorption capacities, suggesting that this microbial community may serve as a target to improve conditions of over- and undernutrition.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Jejunal microorganisms modulate fat digestion and absorption.

References

  1. Arora, T. & Bäckhed, F. J. Intern. Med. 280, 339–349 (2016).

    Article  PubMed  CAS  Google Scholar 

  2. Borgström, B. et al. J. Clin. Invest. 36, 1521–1536 (1957).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Martinez-Guryn, K. et al. Cell Host Microbe 23, 458 (2018).

    Article  PubMed  CAS  Google Scholar 

  4. Bäckhed, F. et al. Proc. Natl Acad. Sci. USA 104, 979–984 (2007).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Zoetendal, E. G. et al. ISME J. 6, 1415–1426 (2012).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. El Aidy, S. et al. Curr. Opin. Biotech. 32, 14–20 (2015).

    Article  PubMed  CAS  Google Scholar 

  7. El Aidy, S. et al. Gut 62, 1306–1314 (2013).

    Article  PubMed  CAS  Google Scholar 

  8. Bauer, P. V. et al. Cell Metab. 27, 572–587 (2018).

    Article  PubMed  CAS  Google Scholar 

  9. Bauer, P. V. et al. Cell Metab. 27, 101–117 (2018).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Host Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands

    Michiel Kleerebezem

Authors
  1. Michiel Kleerebezem
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Michiel Kleerebezem.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kleerebezem, M. Microbial metabolic gatekeeping in the jejunum. Nat Microbiol 3, 650–651 (2018). https://doi.org/10.1038/s41564-018-0172-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41564-018-0172-0

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing