Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

DIAGNOSTICS

TB diagnosis from the Dark Ages to fluorescence

Effective treatment and eradication of tuberculosis requires highly sensitive and specific, easy-to-use detection methods. New advances in molecular tools and technology are driving improved tuberculosis diagnostics, including ways to rapidly identify highly drug-resistant infections.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Fig. 1: Detecting drug resistance with the GeneXpert 2.0.

References

  1. Smith, S. E., Kurbatova, E. V., Cavanaugh, J. S. & Cegielski, J. P. Int. J. Tuberc. Lung. Dis. 16, 203–205 (2012).

    CAS  Article  Google Scholar 

  2. Kunkel, A. et al. BMC Infect. Dis. 16, 282 (2016).

    Article  Google Scholar 

  3. Catanzaro, A. et al. PLoS ONE 10, e0136861 (2015).

    Article  Google Scholar 

  4. Boehme, C. C. et al. New Engl. J. Med. 363, 1005–1015 (2010).

    CAS  Article  Google Scholar 

  5. Tyagi, S. & Kramer, F. R. Nat. Biotechnol. 14, 303–308 (1996).

    CAS  Article  Google Scholar 

  6. Xie, Y. L. et al. New Engl. J. Med. 377, 1043–1054 (2017).

    CAS  Article  Google Scholar 

  7. Yadon, A. N. et al. Nat. Commun. 8, 588 (2017).

    Article  Google Scholar 

  8. Ramirez-Busby, S. M. & Valafar, F. Antimicrob. Agents Ch. 59, 5267–5277 (2015).

    CAS  Article  Google Scholar 

  9. Miotto, P. et al. mBio 5, e01819–01814 (2014).

    CAS  Article  Google Scholar 

  10. Aung, K. J. et al. Int. J. Tuberc. Lung D. 18, 1180–1187 (2014).

    CAS  Article  Google Scholar 

  11. Koser, C. U. et al. Lancet 385, 305–307 (2015).

    Article  Google Scholar 

  12. Quan, T. P. et al. J. Clin. Microbiol. http://doi.org/cjdm (2017).

  13. Satta, G. et al. Clin. Microbiol. Infect. http://doi.org/cjdn (2017).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Eric J. Rubin.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Rubin, E.J. TB diagnosis from the Dark Ages to fluorescence. Nat Microbiol 3, 268–269 (2018). https://doi.org/10.1038/s41564-018-0118-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41564-018-0118-6

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing