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VIRUS PATHOGENESIS

Zika virus targets blood monocytes

Two studies identify circulating monocytes as the primary cellular target of Zika virus infection in human blood. Monocytes are an ideal target as they have the potential to be used as a Trojan horse to infiltrate immune-sheltered tissues, including placenta, testes and the brain, to spread Zika virus.

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Correspondence to Akiko Iwasaki.

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The authors declare no competing financial interests.

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Further reading

Fig. 1: Zika virus infection of blood cells.