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VIRUS PATHOGENESIS

Zika virus targets blood monocytes

Nature Microbiology volume 2, pages 1460–1461 (2017)Cite this article

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Two studies identify circulating monocytes as the primary cellular target of Zika virus infection in human blood. Monocytes are an ideal target as they have the potential to be used as a Trojan horse to infiltrate immune-sheltered tissues, including placenta, testes and the brain, to spread Zika virus.

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Fig. 1: Zika virus infection of blood cells.

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Authors and Affiliations

  1. Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06520, USA

    Kellie Ann Jurado & Akiko Iwasaki

  2. The Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA

    Akiko Iwasaki

Authors
  1. Kellie Ann Jurado
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  2. Akiko Iwasaki
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Correspondence to Akiko Iwasaki.

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The authors declare no competing financial interests.

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Jurado, K.A., Iwasaki, A. Zika virus targets blood monocytes. Nat Microbiol 2, 1460–1461 (2017). https://doi.org/10.1038/s41564-017-0049-7

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