Finding life’s missing pieces

The Uncultivated Bacteria and Archaea dataset is a foundational collection of 7,903 genomes from uncultivated microorganisms. It highlights how microbial diversity is readily recovered using current tools and existing metagenomic datasets to help piece together the tree of life.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1: Reconstruction of nearly 8,000 microbial genomes from a range of environments provides previously missing pieces of the tree of life.


  1. 1.

    Falkowski, P. G., Fenchel, T. & Delong, E. F. Science 320, 1034–1039 (2008).

    CAS  Article  PubMed  Google Scholar 

  2. 2.

    Bowers, R. M. et al. Nat. Biotech. 35, 725–731 (2017).

    CAS  Article  Google Scholar 

  3. 3.

    Solden, L. M., Lloyd, K. & Wrighton, K. C. Curr. Opin. Microbiol. 31, 217–226 (2016).

    Article  PubMed  Google Scholar 

  4. 4.

    Parks, D. H. et al. Nat. Microbiol. (2017).

    Google Scholar 

  5. 5.

    Antharaman, K. et al. Nat. Commun. 7, 13219 (2016).

    Article  Google Scholar 

  6. 6.

    Konstantinidis, K. T., Rossello-Mora, R. & Amann, R. ISME J. (2017).

  7. 7.

    Rinke, C. et al. Nature 499, 431–437 (2013).

    CAS  Article  PubMed  Google Scholar 

  8. 8.

    Brown, C. T. et al. Nature 523, 208–211 (2015).

    CAS  Article  PubMed  Google Scholar 

  9. 9.

    Hug, L. A. et al. Nat. Microbiol. 1, 16048 (2016).

    CAS  Article  PubMed  Google Scholar 

  10. 10.

    Vanwonterghem, I. et al. Nat. Microbiol. 1, 16170 (2016).

    CAS  Article  PubMed  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Kelly C. Wrighton.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Solden, L.M., Wrighton, K.C. Finding life’s missing pieces. Nat Microbiol 2, 1458–1459 (2017).

Download citation