The goal of malaria eradication is threatened by drug resistance. Now, two studies characterize Plasmodium falciparum PKG inhibitors and hexahydroquinolines as antimalarial compounds that could block transmission and help mitigate the risk of parasite escape via drug resistance.
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Diagana, T., Jones, C. Hitting malaria where it hurts. Nat Microbiol 2, 1336–1337 (2017). https://doi.org/10.1038/s41564-017-0036-z
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DOI: https://doi.org/10.1038/s41564-017-0036-z