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ANTIVIRALS

New options to treat influenza B

Influenza B virus causes substantial illness globally, particularly in children. Treatment options are limited, as the most widely used antiviral drug appears to be less effective than against influenza A. A new antibody targeting the influenza B neuraminidase shows promise in mice as a therapeutic option.

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References

  1. 1.

    Rolfes, M. et al. Estimated Influenza Illnesses, Medical Visits, Hospitalizations, and Deaths Averted by Vaccination in the United States (CDC, 2016).

  2. 2.

    Lafond, K. E. et al. PLoS Med. 13, e1001977 (2016).

  3. 3.

    Paul Glezen, W., Schmier, J. K., Kuehn, C. M., Ryan, K. J. & Oxford, J. Am. J. Public Health. 103, e43–e51 (2013).

  4. 4.

    Tran, D. et al. Pediatrics http://doi.org/f85zsf (2016).

  5. 5.

    Wohlbold, T. J. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-017-0011-8 (2017).

  6. 6.

    Sugaya, N. et al. Clin. Infect. Dis. 44, 197–202 (2017).

  7. 7.

    Kallewaard, N. L. et al. Cell 166, 596–608 (2016).

  8. 8.

    Muthuri, S. G. et al. Lancet Respir. Med. 2, 395–404 (2014).

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Correspondence to Kanta Subbarao.

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The authors declare no competing financial interests.

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Fig. 1: Roles of viral neuraminidase and anti-neuraminidase monoclonal antibodies in influenza virus infection.