Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Biosensors

A refresh-in-sensing reusable biosensor

Nature Materials (2024)Cite this article

Subjects

An electrochemical biosensor capable of detecting low levels of cancer biomarkers is reusable over 200 regeneration cycles without compromising device sensitivity and accuracy.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Refresh-in-sensing DM-OECT for reusable EGFR detection.

References

  1. Singh, S., Podder, P. S., Russo, M., Henry, C. & Cinti, S. Lab Chip 23, 44–61 (2022).

    Article  PubMed  Google Scholar 

  2. Cai, R. et al. Nat. Commun. 15, 1689 (2024).

  3. Guo, K. et al. Nat. Biomed. Eng. 5, 666–677 (2021).

    Article  CAS  PubMed  Google Scholar 

  4. Liu, H. et al. Adv. Sci. 11, 2305347 (2024).

    Article  CAS  Google Scholar 

  5. Marks, A., Griggs, S., Gasparini, N. & Moser, M. Adv. Mater. Interf. 9, 2102039 (2022).

    Article  CAS  Google Scholar 

  6. Fumeaux, N., Almeida, C. P., Demuru, S. & Briand, D. Sci. Rep. 13, 11467 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Wu, J., Liu, H., Chen, W., Ma, B. & Ju, H. Nat. Rev. Bioeng. 1, 346–360 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Jiang, Z. et al. Nat. Mater. https://doi.org/10.1038/s41563-024-01970-5 (2024).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Aleman, J., Kilic, T., Mille, L. S., Shin, S. R. & Zhang, Y. S. Nat. Protoc. 16, 2564–2593 (2021).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, MA, USA

    Salvador Gallegos-Martinez & Yu Shrike Zhang

  2. Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA

    Yu Shrike Zhang

  3. Broad Institute of MIT and Harvard, Cambridge, MA, USA

    Yu Shrike Zhang

Authors
  1. Salvador Gallegos-Martinez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yu Shrike Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yu Shrike Zhang.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gallegos-Martinez, S., Zhang, Y.S. A refresh-in-sensing reusable biosensor. Nat. Mater. (2024). https://doi.org/10.1038/s41563-024-02001-z

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41563-024-02001-z

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing