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CANCER DIAGNOSIS

A ‘Swiss army knife’ probe for metastatic cancers

A nanosensor probe that combines a tumour-targeting peptide, a diagnostic reporter and an imaging contrast agent enables early diagnosis, precision imaging, disease stratification and downstream therapeutic response monitoring of metastatic cancer.

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Fig. 1: A multimodal imaging probe for detection and monitoring of metastatic cancers.

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Correspondence to Matthew Bogyo.

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Competing interests

M.B. is a founder and consultant for Akrotome Imaging Inc. and is a consultant at Vergent Bioscience. Both companies are developing optical contrast agents that target lysosomal cysteine protease for imaging tumours during surgery.

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Bogyo, M. A ‘Swiss army knife’ probe for metastatic cancers. Nat. Mater. 20, 1312–1314 (2021). https://doi.org/10.1038/s41563-021-01105-0

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