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Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

The Original Article was published on 18 February 2021

Correction to: Nature Materials https://doi.org/10.1038/s41563-021-00919-2, published online 18 February 2021.

In the version of this Article originally published, the captions for Extended Data Figs. 1, 2 and 3 were in the wrong order and did not correspond to their associated figures. The correct captions are listed below and the Article has been corrected accordingly. In addition, the cell line MCF7 was mistakenly written as ‘MCF7A’ in seven instances in the main text, Methods and Extended Data Fig. 4 caption, and as ‘MCF10A’ in one instance in the ‘Author contributions’ section; these errors have now been corrected.

Extended Data Fig. 1 | MDCK WT behave as an extensile system. a, Kymograph of a short junction (<10μm) (top) and long junction (>15μm) (bottom) before and after laser ablation. b, Recoil velocity after laser ablation for short (<10μm) (n=9) (N=4), medium (10-15μm) (n=13)(N=4) and long junctions (> 15μm) (n=12) (N=6). n, is the number of junctions ablated and N is the number of independent experiments from which these results were obtained. Error bars represent the standard deviation. ANOVA test was performed leading to *p<0.05, **p<0.01, ***p<0.001 and ****p<0.0001. Scale bars, 20μm.

Extended Data Fig. 2 | MDCK WT behaves as an extensile system and MDCK E-cadherin KO behave as a contractile system. a,b, Orientation field (left) and velocity vectors (right) around a single comet-shaped (+1/2) defect (a) and trefoil (-1/2) defect obtained from WT (top) and E-cadherin KO (bottom) monolayers. c,d, Trajectory of several comet (+1/2) (left) and trefoil (-1/2) (right) shaped defects obtained from MDCK WT (c) and MDCK E-cadherin KO (d) monolayers. Scale bars: 40μm.

Extended Data Fig. 3 | Fibroblasts behave as a 2D contractile active nematic. a, Average yy- and xy-components of strain rate map around +1/2 defect obtained from experiments (left and middle respectively) and corresponding average flow field (right) (n = 1489 defects from 2 independent experiments) for NIH3T3 cells. Colour code is positive for stretching and negative for shrinkage. b, Average yy (left)-, xy (middle)- and isotropic (right) components of stress around a +1/2 defect obtained from experiments for NIH3T3 (n = 1,428 defects from 2 independent experiments).

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Correspondence to Amin Doostmohammadi or René-Marc Mège or Julia M. Yeomans or Benoît Ladoux.

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Balasubramaniam, L., Doostmohammadi, A., Saw, T.B. et al. Author Correction: Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers. Nat. Mater. 20, 1167 (2021). https://doi.org/10.1038/s41563-021-00974-9

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