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A selective ionic rectifier

Creation of bioinspired ion channels that separate ions without compromising selectivity, conductivity or rectification ability has long been a challenge. Integration of metal–organic frameworks into asymmetric nanopore membranes overcomes this limitation.

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Fig. 1: Hybrid polymeric/MOF membrane.


  1. 1.

    Doyle, D. A. et al. Science 280, 69–77 (1998).

    CAS  Article  Google Scholar 

  2. 2.

    Siwy, Z. S. Adv. Funct. Mater. 16, 735–746 (2006).

    CAS  Article  Google Scholar 

  3. 3.

    Siwy, Z., Heins, E., Harrell, C. C., Kohli, P. & Martin, C. R. J. Am. Chem. Soc. 126, 10850–10851 (2004).

    CAS  Article  Google Scholar 

  4. 4.

    Zhou, Y., Morais-Cabral, J. H., Kaufman, A. & MacKinnon, R. Nature 414, 43–48 (2001).

    CAS  Article  Google Scholar 

  5. 5.

    Abraham, J. et al. Nat. Nanotechnol. 12, 546–550 (2017).

    CAS  Article  Google Scholar 

  6. 6.

    Lu, J. et al. Nat. Mater. (2020).

  7. 7.

    Li, X. et al. Nat. Commun. 10, 2490 (2019).

    Article  Google Scholar 

  8. 8.

    Zhang, Z., Wen, L. & Jiang, L. Chem. Soc. Rev. 47, 322–356 (2018).

    CAS  Article  Google Scholar 

  9. 9.

    Eisenman, G. & Horn, R. J. Membrane Biol. 76, 197–225 (1983).

    CAS  Article  Google Scholar 

  10. 10.

    Legrand, A. et al. Chem. Sci. 10, 10833–10842 (2019).

    CAS  Article  Google Scholar 

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Correspondence to Shuhei Furukawa.

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Legrand, A., Furukawa, S. A selective ionic rectifier. Nat. Mater. 19, 701–702 (2020).

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