Predicting post-stroke aphasia from brain imaging

Stroke can lead to debilitating consequences, including loss of language. An important goal of stroke research is to use machine learning to predict outcomes and response to therapy. A new study compares different approaches to predicting post-stroke outcomes and highlights the need for systematic optimization and validation to ultimately translate scientific insights to clinical settings.

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  1. 1.

    Engelter, S. T. et al. Stroke 37, 1379–1384 (2006).

    Article  Google Scholar 

  2. 2.

    Hilari, K. Disabil. Rehabil. 33, 211–218 (2011).

    Article  Google Scholar 

  3. 3.

    Breitenstein, C. et al. Lancet 389, 1528–1538 (2017).

    Article  Google Scholar 

  4. 4.

    Halai, A. D. Nat. Hum. Behav. (2020).

    Article  PubMed  Google Scholar 

  5. 5.

    Hope, T. M. H., Seghier, M. L., Leff, A. P. & Price, C. J. Neuroimage Clin 2, 424–433 (2013).

    Article  Google Scholar 

  6. 6.

    Yourganov, G., Smith, K. G., Fridriksson, J. & Rorden, C. Cortex 73, 203–215 (2015).

    Article  Google Scholar 

  7. 7.

    Plowman, E., Hentz, B. & Ellis, C. Jr. J. Eval. Clin. Pract 18, 689–694 (2012).

    Article  Google Scholar 

  8. 8.

    Halai, A. D., Woollams, A. M. & Lambon Ralph, M. A. Cortex 86, 275–289 (2017).

    Article  Google Scholar 

  9. 9.

    Halai, A. D., Woollams, A. M. & Lambon Ralph, M. A. Neuroimage Clin 19, 1–13 (2018).

    Article  Google Scholar 

  10. 10.

    Seghier, M. L. et al. Neuroimage 124 Pt B, 1208–1212 (2016).

    Article  Google Scholar 

Download references

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Correspondence to Monica D. Rosenberg.

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Rosenberg, M.D., Song, H. Predicting post-stroke aphasia from brain imaging. Nat Hum Behav (2020).

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