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Neuroscience: Rationality, uncertainty, dopamine

Recent theories propose that perceptions, decisions, and behaviour rely on many rational neural observers that work to predict the value of stimuli and actions. This Bayesian framework has now advanced into new territory through a study of dopamine's influence on the integration of sensory (new) and prior (old) information in Parkinson's disease.

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References

  1. Friston, K. J. Nat. Rev. Neurosci. 11, 127–138 (2010).

    Article  CAS  PubMed  Google Scholar 

  2. Fiorillo, C. D. PLoS ONE 3, e3298 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Körding, K. P. & Wolpert, D. M. Nature 427, 244–247 (2004).

    Article  PubMed  Google Scholar 

  4. Kim, J. K. & Fiorillo, C. D. Nat. Commun. 8, 14566 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Sterling, P. & Laughlin, S. B. Principles of Neural Design (MIT Press, 2015).

    Book  Google Scholar 

  6. Vilares, I. & Kording, K. P. Nat. Hum. Behav. 1, 0129 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Schultz, W. Physiol. Rev. 95, 853–951 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Friston, K. J. et al. PLoS Comput. Biol. 8, e1002327 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Galea, J. M., Bestmann, S., Beigi, M., Jahanshahi, M. & Rothwell, J. C. J. Neurosci. 32, 542–550 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Fiorillo, C. D. Information 3, 175–203 (2012).

    Article  Google Scholar 

Download references

Acknowledgements

The research was supported by a grant from the National Research Foundation of Korea (2015-R1A2A2A01004185).

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Correspondence to Christopher D. Fiorillo.

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Fiorillo, C. Neuroscience: Rationality, uncertainty, dopamine. Nat Hum Behav 1, 0158 (2017). https://doi.org/10.1038/s41562-017-0158

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