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The journey of bacterial genes

Analysis of the dynamics of transposons that encode resistance to different antibiotics shows that the movement of genes under positive selection from the chromosome to mobile genetic elements such as plasmids can be beneficial in bacteria. Once integrated into plasmids, these genes can spread by horizontal gene transfer.

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Fig. 1: Effect of positive selection on chromosome-to-plasmid transposition events.


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Correspondence to Alvaro San Millan.

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San Millan, A. The journey of bacterial genes. Nat Ecol Evol 6, 498–499 (2022).

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