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EXPERIMENTAL EVOLUTION

Life on the frontline reveals constraints

The existence of trade-offs between traits under selection is a fundamental concept in evolutionary biology. Analysis of a densely sampled collection of adaptive mutations in yeast reveals that no single mutation can allow it to overcome detected trade-offs between key traits under selection.

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Fig. 1: Trade-offs between traits in yeast.

References

  1. 1.

    MacArthur, R. H. & Wilson, E. O. The Theory of Island Biogeography Vol. 1 (Princeton Univ. Press, 2001).

  2. 2.

    Li, Y., Petrov, D. A. & Sherlock, G. Nat. Ecol. Evol. https://doi.org/10.1038/s41559-019-0993-0 (2019).

    Article  PubMed  Google Scholar 

  3. 3.

    Rolland, F., Winderickx, J. & Thevelein, J. M. FEMS Yeast Res. 2, 183–201 (2002).

    CAS  Article  Google Scholar 

  4. 4.

    Shoval, O. et al. Science 336, 1157–1160 (2012).

    CAS  Article  Google Scholar 

  5. 5.

    Fitzsimmons, J. M., Schoustra, S. E., Kerr, J. T. & Kassen, R. Evol. Ecol. 24, 227–236 (2010).

    Article  Google Scholar 

  6. 6.

    Reding-Roman, C. et al. Nat. Ecol. Evol. 1, 0050 (2017).

    Article  Google Scholar 

  7. 7.

    Gibson, B. et al. FEMS Yeast Res. 17, fox038 (2017).

    Article  Google Scholar 

  8. 8.

    Brennan, G. L., Colegrave, N. & Collins, S. Proc. Natl Acad. Sci. USA 114, 9930–9935 (2017).

    CAS  Article  Google Scholar 

  9. 9.

    Palmer, A. C. et al. Nat. Commun. 6, 7385 (2015).

    CAS  Article  Google Scholar 

  10. 10.

    Eberlein, C. et al. Nat. Commun. 10, 923 (2019).

    Article  Google Scholar 

  11. 11.

    Mori, M., Marinari, E. & De Martino, A. npj Syst. Biol. Appl. 5, 16 (2019).

    Article  Google Scholar 

Download references

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Correspondence to Danna R. Gifford.

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Gifford, D.R. Life on the frontline reveals constraints. Nat Ecol Evol 3, 1501–1502 (2019). https://doi.org/10.1038/s41559-019-1010-3

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