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A call for integrated metastatic management

Nature Ecology & Evolution volume 3, pages 996–998 (2019)Cite this article

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Metastatic disease remains invariably fatal. Until truly curative therapies are developed, can clinical oncology benefit from lessons learned in pest management?

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Fig. 1: Integrated metastatic management.

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References

  1. Jemal, A. et al. J. Natl. Cancer Inst. 109, djx030 (2017).

    Article  Google Scholar 

  2. Gatenby, R. A. & Brown, J. S. Cold Spring Harb. Perspect. Med. 1, a033415 (2018).

    Article  Google Scholar 

  3. McGranahan, N. & Swanton, C. Cell 168, 613–628 (2017).

    Article  CAS  Google Scholar 

  4. Peshin, R. & Dhawan, A.K. Integrated Pest Management: Innovation and Development Process (Springer, 2009).

  5. Talekar, N. & Shelton, A. Annu. Rev. Entomol. 38, 275–301 (1993).

    Article  Google Scholar 

  6. Kogan, M. Annu. Rev. Entomol. 43, 243–270 (1998).

    Article  CAS  Google Scholar 

  7. REX Consortium. Trends Ecol. Evol. 28, 110–118 (2013).

    Article  Google Scholar 

  8. Aktipis, C. A., Boddy, A. M., Gatenby, R. A., Brown, J. S. & Maley, C. C. Nat. Rev. Cancer 13, 883–892 (2013).

    Article  CAS  Google Scholar 

  9. Barzman, M. et al. Agron. Sustain. Dev. 35, 1199–1215 (2015).

    Article  Google Scholar 

  10. McGuire, S. Adv. Nutr. 7, 418–419 (2016).

    Article  Google Scholar 

  11. Norton, L. & Simon, R. Cancer Treat. Rep. 61, 1307–1317 (1977).

    CAS  PubMed  Google Scholar 

  12. Gatenby, R. A., Silva, A. S., Gillies, R. J. & Frieden, B. R. Cancer Res. 69, 4894–4903 (2009).

    Article  CAS  Google Scholar 

  13. Graham, L. J. et al. J. Cancer 5, 58–68 (2014).

    Article  Google Scholar 

  14. Krebs, M. G. et al. Nat. Rev. Clin. Oncol. 11, 129–144 (2014).

    Article  CAS  Google Scholar 

  15. Chaudhuri, A. A. et al. Cancer Discov. 7, 1394–1403 (2017).

    Article  CAS  Google Scholar 

  16. Murtaza, M. et al. Nature 497, 108–112 (2013).

    Article  CAS  Google Scholar 

  17. Gillies, R. J., Kinahan, P. E. & Hricak, H. Radiology 278, 563–577 (2016).

    Article  Google Scholar 

  18. Holt, R. D. & Hochberg, M. E. Ecology 78, 1673–1683 (1997).

    Article  Google Scholar 

  19. Kelderman, S., Schumacher, T. N. & Haanen, J. B. Mol. Oncol. 8, 1132–1139 (2014).

    Article  CAS  Google Scholar 

  20. Kramer, M. G., Masner, M., Ferreira, F. A. & Hoffman, R. M. Front. Microbiol. 9, 16 (2018).

    Article  Google Scholar 

  21. Fukuhara, H., Ino, Y. & Todo, T. Cancer Sci. 107, 1373–1379 (2016).

    Article  CAS  Google Scholar 

  22. Roviello, G. et al. Eur. J. Cancer 75, 245–258 (2017).

    Article  CAS  Google Scholar 

  23. Clézardin, P., Ebetino, F. H. & Fournier, P. G. Cancer Res. 65, 4971–4974 (2005).

    Article  Google Scholar 

  24. Robey, I. F. et al. Cancer Res. 69, 2260–2268 (2009).

    Article  CAS  Google Scholar 

  25. Moen, I. & Stuhr, L. E. Target. Oncol. 7, 233–242 (2012).

    Article  Google Scholar 

  26. Pajonk, F. & Vlashi, E. Semin. Radiat. Oncol. 23, 237–241 (2013).

    Article  Google Scholar 

  27. Schwartzberg, L., Kim, E. S., Liu, D. & Schrag, D. Am. Soc. Clin. Oncol. Educ. Book 37, 160–169 (2017).

    Article  Google Scholar 

  28. Meng, S. et al. Proc. Natl Acad. Sci. USA 101, 9393–9398 (2004).

    Article  CAS  Google Scholar 

  29. Calabrese, E. & Baldwin, L. Hum. Exp. Toxicol. 21, 91–97 (2002).

    Article  CAS  Google Scholar 

  30. Jørgensen, K. M. et al. Antimicrob. Agents Chemother. 57, 4215–4221 (2013).

    Article  Google Scholar 

  31. Bacevic, K. et al. Nat. Commun. 8, 1995 (2017).

    Article  Google Scholar 

  32. Enriquez-Navas, P. M. et al. Sci. Transl. Med. 24, 327 (2016).

    Google Scholar 

  33. Zhang, J., Cunningham, J. J., Brown, J. S. & Gatenby, R. A. Nat. Commun. 8, 1816 (2017).

    Article  Google Scholar 

  34. Antonia, S. J. et al. Clin. Cancer Res. 12, 878–887 (2006).

    Article  CAS  Google Scholar 

  35. Greene, S. E. & Reid, A. Microbe Magazine 8, 279–285 (2013).

    Article  Google Scholar 

  36. Blumenthal, G. M., Birnkrant, D. & Pazdur, R. Clin. Cancer Res. 24, 2491–2492 (2018).

    Article  Google Scholar 

  37. Woods, R. J. & Read, A. F. Evol. Med. Public Health 2015, 281–288 (2015).

    Article  Google Scholar 

  38. Nichol, D. et al. Nat. Commun. 10, 334 (2019).

    Article  Google Scholar 

  39. Waller, P. J. Anim. Feed Sci. Technol. 126, 277–289 (2006).

    Article  Google Scholar 

  40. Beier, J. C. et al. Malar. J. 7, S4 (2008).

    Article  Google Scholar 

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Acknowledgements

I would like to thank R. A. Gatenby, J. S. Brown, K. Staňková, V. Forster and K. Pienta for providing insight and expertise that greatly improved this work.

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Authors and Affiliations

  1. Department of Integrated Mathematical Oncology, Moffitt Cancer Center & Research Institute, Tampa, FL, USA

    Jessica J. Cunningham

  2. Department of Data Science and Knowledge Engineering, Maastricht University, Maastricht, the Netherlands

    Jessica J. Cunningham

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  1. Jessica J. Cunningham
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Correspondence to Jessica J. Cunningham.

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The author declares no competing interests.

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Cunningham, J.J. A call for integrated metastatic management. Nat Ecol Evol 3, 996–998 (2019). https://doi.org/10.1038/s41559-019-0927-x

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