Three studies presenting genomes and transcriptomes from different life stages of nearly all major lineages of medusozoans present radically different gene expression profiles between life cycle stages and many medusa-specific genes.
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Schnitzler, C.E. What makes a jellyfish. Nat Ecol Evol 3, 724–725 (2019). https://doi.org/10.1038/s41559-019-0872-8