Virology

Influenza evolution with little host selection

Influenza viruses undergo rapid antigenic evolution. Analysis of a large dataset of influenza virus sequences, using host age as a proxy for immune experience, shows no evidence for immune positive selection driving antigenic evolution in individual infected humans.

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Correspondence to Thomas C. Friedrich.

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Braun, K.M., Friedrich, T.C. Influenza evolution with little host selection. Nat Ecol Evol 3, 159–160 (2019). https://doi.org/10.1038/s41559-018-0782-1

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