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IMMUNE EVOLUTION

Sick if you do, sick if you don’t

Nature Ecology & Evolution volume 1, pages 1602–1603 (2017)Cite this article

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The immune system must distinguish self from non-self, but an imbalanced reaction in either direction can lead to immunopathology or severe infection. A new model incorporating host life history predicts which error will be more tolerated.

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Fig. 1: Discrimination involves a tradeoff between two types of error.

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Authors and Affiliations

  1. Department of Ecology and Evolution, University of Chicago, 1101 E 57th Street, Chicago, IL, 60637, USA

    Sarah Cobey

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  1. Sarah Cobey
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Correspondence to Sarah Cobey.

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The author declares no competing financial interests.

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Cobey, S. Sick if you do, sick if you don’t. Nat Ecol Evol 1, 1602–1603 (2017). https://doi.org/10.1038/s41559-017-0342-0

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