Some invasive hymenopteran social insects found new populations with very few reproductive individuals. This is despite the high cost of founder effects for such insects, which generally require heterozygosity at a single locus—the complementary sex determiner, csd—to develop as females. Individuals that are homozygous at csd develop as either infertile or subfertile diploid males or not at all. Furthermore, diploid males replace the female workers that are essential for colony function. Here we document how the Asian honey bee (Apis cerana) overcame the diploid male problem during its invasion of Australia. Natural selection prevented the loss of rare csd alleles due to genetic drift and corrected the skew in allele frequencies caused by founder effects to restore high average heterozygosity. Thus, balancing selection can alleviate the genetic load at csd imposed by severe bottlenecks, and so facilitate invasiveness.
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We thank the Queensland Department of Agriculture and Fisheries, Queensland Biosecurity, Australian Government Department of Agriculture and Water Resources, Cairns Regional Bee Club, E. Remnant, R. Stephens, R. Swenson, M. Gorton and M. Damon for their assistance. R.G. is supported by a University of Sydney Postdoctoral Fellowship. Research funding came from Australian Research Council DP150101985.
The authors declare no competing financial interests.
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Gloag, R., Ding, G., Christie, J. et al. An invasive social insect overcomes genetic load at the sex locus. Nat Ecol Evol 1, 0011 (2017). https://doi.org/10.1038/s41559-016-0011
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