Deuterated compounds are used in many applications such as mass-spectrometry standards, drugs or in organic light-emitting diodes. Now, hydrogen-activated homogeneous pincer complex catalysts can be used to perform selective alkene deuteration with the cheapest available deuterium source, D2O.
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The authors are employed at Sanofi and hold stocks and shares of the company.
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Tarasewicz, A., Derdau, V. Hydrogenative double-bond deuteration. Nat. Chem. 15, 1332–1333 (2023). https://doi.org/10.1038/s41557-023-01326-7