Aryl ethers are useful intermediates in organic synthesis and are found in countless biologically active compounds. Now, through palladium/norbornene cooperative catalysis and incorporation of a polarity-reversed N–O reagent as the O-electrophile, an efficient arene methoxylation approach has been successfully developed.
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Zhao, K., Gu, Z. Aryl ortho methoxylation. Nat. Chem. 15, 1334–1335 (2023). https://doi.org/10.1038/s41557-023-01323-w