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Illuminating anti-ageing

Therapies that destroy senescent cells could be used to alleviate age-related disease, yet conventional drugs often suffer from low selectivity and unwanted side effects. Now, a photosensitive agent has been developed that is activated in situ in senescent cells, enabling their selective elimination.

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Fig. 1: Activation of the senotherapeutic prodrug KSL0608-Se.


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Correspondence to Jong Seung Kim or Mingle Li.

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The authors declare no competing interests.

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Xu, Y., Kim, J.S. & Li, M. Illuminating anti-ageing. Nat. Chem. 15, 451–452 (2023).

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