Molecular computing programmed with complementary nucleic acid strands allows the construction of sophisticated biomolecular circuits. Now, systems with partially complementary strands have been shown to enable more compact and faster molecular circuits, and may illuminate biological processes.
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The authors declare no competing interests.
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Petersen, P., Tikhomirov, G. Non-complementary computation. Nat. Chem. 15, 9–11 (2023). https://doi.org/10.1038/s41557-022-01115-8