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DNA nanotechnology

Scaling up genelet circuits

DNA nanotechnology and synthetic biology both aim to expand the range of dynamic behaviours exhibited by rationally programmed biomolecules. Now, the programmability of synthetic transcriptional circuits has been improved to enable synthesis of dynamic biomolecular circuits with unmatched complexity.

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Fig. 1: Programming the genelet circuits.


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Correspondence to Jongmin Kim or Friedrich C. Simmel.

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Kim, J., Simmel, F.C. Scaling up genelet circuits. Nat. Chem. 14, 1210–1211 (2022).

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